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\u6b64\u6b21\u6d88\u606f\u4e2d\uff0c\u4e09\u53f6\u8349\u751f\u7269\u91ca\u653e\u51fa\u7684\u4fe1\u53f7\uff0c\u5c55\u793a\u4e86\u5176\u53d1\u5c55\u7684\u97e7\u6027\u548c\u660e\u786e\u7684\u6218\u7565\u65b9\u5411\uff0c\u4ece\u52a0\u5f3a\u9488\u7684\u65b0\u6570\u636e\uff0c\u5230\u5546\u4e1a\u5316\u7684\u5feb\u901f\u63a8\u8fdb\uff0c\u4ee5\u53ca\u5bf9\u75ab\u82d7\u8d5b\u9053\u7684\u4e13\u6ce8\uff0c\u5728\u5e74\u8f7b\u638c\u95e8\u4eba\u6881\u679c\u7684\u5e26\u9886\u4e0b\uff0c\u8d70\u51fa\u4e86\u4e00\u6761\u52c7\u6bc5\u521b\u65b0\u4e4b\u8def\u3002<\/p>\n

\u3000\u3000\u8dd1\u8d62\u65b0\u51a0\u75c5\u6bd2?SCB-2019\u65b0\u6570\u636e \u5e26\u6765\u4fe1\u5fc3\u548c\u5e0c\u671b<\/strong><\/p>\n

\u3000\u3000SARS-CoV-2(\u65b0\u51a0\u75c5\u6bd2)\u662f\u5f15\u53d1COVID-19(\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u80ba\u708e)\u7684RNA\u75c5\u6bd2\uff0c\u5176\u8868\u9762\u6297\u539fS\u86cb\u767d\u5177\u6709\u4e09\u805a\u4f53\u7ed3\u6784\uff0c\u662f\u4e09\u53f6\u8349\u751f\u7269\u75ab\u82d7\u5f00\u53d1\u7684\u4e3b\u8981\u76ee\u6807\u6297\u539f\u3002\u5e94\u7528Trimer-Tag™\u5e73\u53f0\u5f00\u53d1\u4e86SCB-2019\u6297\u539f\uff0c\u5e76\u8054\u5408Dynavax CpG 1018\u4f50\u5242\u548c\u6c22\u6c27\u5316\u94dd(\u94dd\u4f50\u5242)\uff0c\u4e09\u53f6\u8349\u751f\u7269\u5f00\u53d1\u4e86\u91cd\u7ec4\u86cb\u767d\u65b0\u51a0\u5019\u9009\u75ab\u82d7\uff0c\u4e5f\u8ba9\u4e09\u53f6\u8349\u751f\u7269\u6210\u4e3a\u4e1a\u754c\u201c\u9ed1\u9a6c\u201d\u3002<\/p>\n

\u968f\u7740\u65b0\u5965\u5bc6\u514b\u620e\u8c31\u7cfb\u7684\u51fa\u73b0\uff0c\u65b0\u53d8\u5f02\u682a\u9020\u6210\u7684\u5a01\u80c1\u4f9d\u7136\u4e25\u5cfb\uff0c\u4e09\u53f6\u8349\u751f\u7269\u4e0e\u65b0\u51a0\u75c5\u6bd2\u7684\u8d5b\u8dd1\u4ece\u672a\u6b62\u6b65\u3002\u5728\u8fd1\u65e5\u53d1\u5e03\u7684\u516c\u5f00\u6d88\u606f\u4e2d\uff0c\u4e09\u53f6\u8349\u751f\u7269\u5ba3\u5e03\u65b0\u51a0\u901a\u7528\u52a0\u5f3a\u9488\u75ab\u82d7\u6570\u636e\uff1a\u65b0\u7684III\u671f\u6570\u636e\u663e\u793a\u4e86\u5e7f\u8c31\u7684\u4e2d\u548c\u4f5c\u7528\u2014\u2014\u5305\u62ec\u5bf9\u5168\u7403\u4e3b\u5bfc\u7684\u5965\u5bc6\u514b\u620eBA.5\u53d8\u5f02\u682a\u4e9a\u578b\u2014\u2014\u5f3a\u8c03\u4e86SCB-2019(CpG 1018\/\u94dd\u4f50\u5242)\u5728\u4e2d\u56fd\u53ca\u5176\u4ed6\u56fd\u5bb6\u4f5c\u4e3a\u901a\u7528\u52a0\u5f3a\u9488\u7684\u6f5c\u5728\u4f5c\u7528\uff0c\u65e0\u8bba\u4e4b\u524d\u7684\u75ab\u82d7\u63a5\u79cd\u8def\u7ebf\u6216\u662f\u5426\u6709\u611f\u67d3\u53f2\uff0c\u4e14\u9002\u7528\u4e8e\u4e0d\u540c\u5e74\u9f84\u7ec4\uff1a<\/p>\n

III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u4f5c\u4e3a\u65e2\u5f80\u63a5\u79cd\u706d\u6d3b\u75ab\u82d7\u7684\u5f02\u6e90\u52a0\u5f3a\u9488\u6570\u636e\uff1a\u4e09\u53f6\u8349\u751f\u72699\u6708\u5ba3\u5e03\u4e86\u6b63\u5728\u8fdb\u884c\u7684III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u79ef\u6781\u6570\u636e\uff0c\u8bc4\u4f30SCB-2019\u4f5c\u4e3a\u901a\u7528\u65b0\u51a0\u52a0\u5f3a\u9488\u5019\u9009\u75ab\u82d7\u7684\u6548\u679c\u3002\u521d\u6b65\u5206\u6790\u663e\u793a\uff0c\u9488\u5bf9\u5168\u7403\u4e3b\u5bfc\u7684\u5965\u5bc6\u514b\u620eBA.5\u53d8\u5f02\u682a\u4e9a\u578b\u548c\u5965\u5bc6\u514b\u620e\u5176\u4ed6\u53d8\u5f02\u682a\u4e9a\u578b(BA.1\uff0cBA.2)\uff0c\u5728\u65e2\u5f80\u63a5\u79cd\u4e24\u5242\u706d\u6d3b\u75ab\u82d7\u7684\u53d7\u8bd5\u8005\u4e2d\uff0c\u63a5\u79cdSCB-2019\u4f5c\u4e3a\u5f02\u6e90\u7b2c\u4e09\u5242\u76f8\u8f83\u4e8e\u7b2c\u4e09\u5242\u63a5\u79cd\u706d\u6d3b\u75ab\u82d7\u8bf1\u5bfc\u4e86\u9ad85-6\u500d\u7684\u4e2d\u548c\u6297\u4f53\u6c34\u5e73;\u9488\u5bf9\u539f\u59cb\u65b0\u51a0\u6bd2\u682a\u7684\u514d\u75ab\u53cd\u5e94\u9ad812\u500d\u3002<\/p>\n

\u8fd9\u9879\u6b63\u5728\u8fdb\u884c\u7684III\u671f\u7814\u7a76\u8fd8\u5165\u7ec4\u4e86\u4e00\u4e2a\u5b50\u961f\u5217\uff0c\u4ee5\u8bc4\u4f30SCB-2019\u4f5c\u4e3a\u7b2c\u56db\u5242\u52a0\u5f3a\u9488\u5728\u65e2\u5f80\u63a5\u79cd\u4e09\u5242\u706d\u6d3b\u75ab\u82d7\u7684\u4e2a\u4f53\u4e2d\u63a5\u79cd\uff0c\u5bf9\u6bd4\u7b2c\u56db\u9488\u540c\u6e90\u706d\u6d3b\u75ab\u82d7\u52a0\u5f3a\u9488\u7684\u6548\u679c\u3002\u521d\u6b65\u6570\u636e\u9884\u8ba1\u5c06\u57282022\u5e74\u7b2c\u56db\u5b63\u5ea6\u83b7\u5f97\u3002<\/p>\n

II\/III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u663e\u793a\u51fa\u9488\u5bf9\u5965\u5bc6\u514b\u620eBA.5\u5f3a\u52b2\u7684\u4e2d\u548c\u53cd\u5e94\uff1a\u5728\u65e2\u5f80\u63a5\u79cd\u4e24\u5242\u706d\u6d3b\u75ab\u82d7\u7684\u53d7\u8bd5\u8005\u4e2d\uff0c\u63a5\u79cdSCB-2019\u4f5c\u4e3a\u5f02\u6e90\u7b2c\u4e09\u5242\u52a0\u5f3a\u9488\u7684\u6570\u636e\u4e0e8\u6708\u4efd\u516c\u5e03\u7684\u7ed3\u679c\u76f8\u7b26\u5408\uff0c\u5373\u5f53SCB-2019\u4f5c\u4e3a\u540c\u6e90\u7684\u7b2c\u4e09\u5242\u52a0\u5f3a\u9488\uff0c\u6216\u662f\u5bf9\u5148\u524d\u6709\u65b0\u51a0\u611f\u67d3\u53f2\u7684\u4eba\u7fa4\u8fdb\u884c\u63a5\u79cd\uff0c\u5747\u5bf9\u5360\u4e3b\u5bfc\u7684\u5965\u5bc6\u514b\u620eBA.5\u53d8\u5f02\u682a\u4e9a\u578b\u4ea7\u751f\u4e86\u5f3a\u52b2\u7684\u514d\u75ab\u5e94\u7b54\u3002<\/p>\n

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\u6765\u81ea\u5168\u7403II\/III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u79ef\u6781\u7684\u9752\u5c11\u5e74\u4eba\u7fa4\u6570\u636e\uff1a\u4e09\u53f6\u8349\u751f\u7269\u57282022\u5e748\u6708\u5ba3\u5e03\u4e00\u9879\u8bc4\u4f30SCB-2019\u5728\u9752\u5c11\u5e74(12\u81f317\u5c81)\u7fa4\u4f53\u4e2d\u7684\u5173\u952e\u6027II\/III\u671f\u8bd5\u9a8c\uff0c\u8be5\u8bd5\u9a8c\u6210\u529f\u8fbe\u5230\u5176\u4e3b\u8981\u7ec8\u70b9\uff0c\u663e\u793a\u51fa\u826f\u597d\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\uff0c\u8be5\u7ed3\u679c\u4e0e\u4e4b\u524d\u5728\u6210\u5e74\u4eba\u7fa4\u4e2d\u89c2\u5bdf\u5230\u7684\u4e00\u81f4\u3002<\/p>\n

\u3000\u3000\u63a8\u8fdb\u6ce8\u518c\u7533\u8bf7\uff0c\u5168\u529b\u51b2\u523a\u7ec8\u70b9\u7ebf<\/strong><\/p>\n

\u3000\u3000\u5728\u4e0d\u65ad\u8fed\u4ee3\u7814\u53d1\u4ea7\u54c1\u7684\u540c\u65f6\uff0c\u4e09\u53f6\u8349\u751f\u7269\u52a0\u901f\u63a8\u8fdb\u4ea7\u54c1\u6ce8\u518c\u7533\u8bf7\u4e0e\u751f\u4ea7\uff0c\u516c\u53f8\u5bf9\u5916\u5ba3\u5e03\u5bf9\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u3001\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u548c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u7684\u6ce8\u518c\u7533\u8bf7\u9012\u4ea4\u8ba1\u5212\u4e8e2022\u5e74\u7b2c\u56db\u5b63\u5ea6\u5b8c\u6210\u3002<\/p>\n

\u5411\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u9012\u4ea4\u7684\u6ce8\u518c\u7533\u8bf7(\u4e09\u53f6\u8349\u751f\u7269\u957f\u5174\u751f\u4ea7\u57fa\u5730)\uff1a\u4e09\u53f6\u8349\u751f\u7269\u4f4d\u4e8e\u957f\u5174\u7684\u81ea\u6709\u751f\u4ea7\u57fa\u5730\u73b0\u5df2\u5b8c\u6210\u4e86\u4e4b\u524d\u786e\u5b9a\u7684\u8bbe\u65bd\u8c03\u6574\u548c\u5b8c\u5584\u5de5\u4f5c\u3002\u4e09\u53f6\u8349\u751f\u7269\u4fdd\u6301\u7740\u4e0e\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u7684\u79ef\u6781\u6c9f\u901a\uff0c\u8fdb\u884cSCB-2019\u7684\u9644\u6761\u4ef6\u751f\u7269\u5236\u5242\u8bb8\u53ef\u7684\u6eda\u52a8\u7533\u8bf7\u9012\u4ea4\uff0c\u76f8\u5173\u7684\u5173\u952e\u6c9f\u901a\u548c\u6d41\u7a0b\u5de5\u4f5c\u5df2\u4e8e\u8fd1\u671f\u5b8c\u6210\u6216\u6b63\u5728\u8fdb\u884c\u4e2d\u3002\u5411\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u7684\u6eda\u52a8\u9012\u4ea4\u9884\u8ba1\u4e8e2022\u5e74\u7b2c\u56db\u5b63\u5ea6\u5b8c\u6210\u3002<\/p>\n

\u5411\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u548c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u9012\u4ea4\u7684\u6ce8\u518c\u7533\u8bf7(\u4e09\u53f6\u8349\u751f\u7269\u7684CDMO\u751f\u4ea7\u57fa\u5730)\uff1a2022\u5e749\u6708\uff0c\u4e09\u53f6\u8349\u751f\u7269\u7684\u5408\u540c\u5f00\u53d1\u751f\u4ea7\u5546(CDMO)\u83b7\u5f97\u6b27\u76dfGMP\u8ba4\u8bc1\uff0c\u7528\u4e8e\u751f\u4ea7\u65b0\u51a0\u5019\u9009\u75ab\u82d7SCB-2019(CpG 1018\/\u94dd\u4f50\u5242)\u3002\u8be5\u6b27\u76dfGMP\u8ba4\u8bc1\u4e0e\u516c\u53f8\u5411\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u9012\u4ea4\u7684\u6ce8\u518c\u7533\u8bf7\u76f8\u5173\u8054\uff0c\u4e3a\u8be5CDMO\u6210\u529f\u901a\u8fc7\u7231\u5c14\u5170\u536b\u751f\u4ea7\u54c1\u76d1\u7ba1\u5c40\u6838\u67e5\u540e\u83b7\u5f97\uff0c\u6807\u5fd7\u7740SCB-2019\u7684\u751f\u4ea7\u7b26\u5408\u6b27\u76df\u7684\u8d28\u91cf\u548c\u5b89\u5168\u6807\u51c6\u3002\u5728CDMO\u751f\u4ea7\u57fa\u5730\u8fdb\u884c\u7684SCB-2019\u751f\u4ea7\u76f8\u5173\u7684\u6280\u672f\u8f6c\u79fb\u6d3b\u52a8\u5df2\u4e8e2022\u5e74\u7b2c\u4e09\u5b63\u5ea6\u5b8c\u6210\uff0c\u9884\u8ba1\u4e8e2022\u5e74\u7b2c\u56db\u5b63\u5ea6\u5b8c\u6210\u5411\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u548c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u9012\u4ea4\u6ce8\u518c\u7533\u8bf7\u3002<\/p>\n

\u5411\u5176\u4ed6\u56fd\u5bb6\u9012\u4ea4\u7684\u6ce8\u518c\u7533\u8bf7\uff1a\u57282022\u5e74\u7b2c\u4e09\u5b63\u5ea6\uff0c\u4e09\u53f6\u8349\u751f\u7269\u4e0e\u5df4\u897f\u548c\u5370\u5ea6\u5c3c\u897f\u4e9a\u7684\u6ce8\u518c\u673a\u6784\u4e3e\u884c\u4e86\u9012\u4ea4\u6ce8\u518c\u7533\u8bf7\u76f8\u5173\u7684\u4f1a\u8bae\uff0c\u8fd9\u662f\u4e09\u53f6\u8349\u751f\u7269\u6b63\u5728\u8fdb\u884c\u4e2d\u7684\u8ba1\u5212\u7684\u4e00\u90e8\u5206\uff0c\u5373\u6218\u7565\u6027\u5730\u5728\u4e00\u4e9b\u56fd\u5bb6\u9012\u4ea4\u6ce8\u518c\u7533\u8bf7\u4ee5\u53ca\u62df\u5b9a\u6f5c\u5728\u7684\u53cc\u8fb9\u4f9b\u5e94\u534f\u8bae\u3002<\/p>\n

\u4e2d\u56fd\u5546\u4e1a\u5316\u4e0a\u5e02\u7684\u51c6\u5907\uff1a\u57fa\u4e8e\u6b63\u5728\u8fdb\u884c\u7684\u6ce8\u518c\u7533\u8bf7\u7684\u9012\u4ea4\u3001\u79ef\u6781\u7684\u5f02\u6e90\u52a0\u5f3a\u9488\u7ed3\u679c\uff0c\u4ee5\u53ca\u6f5c\u5728\u7684\u7b2c\u56db\u5242\u52a0\u5f3a\u9488\u63a8\u5e7f\uff0c\u4e09\u53f6\u8349\u751f\u7269\u4e00\u76f4\u79ef\u6781\u51c6\u5907\uff0c\u4ee5\u4fbf\u5728\u83b7\u5f97\u6ce8\u518c\u6279\u51c6\u540e\u5b9e\u73b0\u5546\u4e1a\u5316\u4e0a\u5e02\u3002\u4e09\u53f6\u8349\u751f\u7269\u5df2\u7ecf\u6218\u7565\u6027\u5730\u5728\u4e00\u4e9b\u4e3b\u8981\u7701\u4efd\u5f00\u5c55\u4e86\u5927\u91cf\u7684\u5b9e\u5730\u5de5\u4f5c\uff0c\u5e76\u7ee7\u7eed\u4e0e\u76d1\u7ba1\u673a\u6784\u4fdd\u6301\u6c9f\u901a\u3002\u968f\u7740\u65b0\u51a0\u75c5\u6bd2\u7684\u6301\u7eed\u6f14\u53d8\u548c\u5176\u4ed6\u56fd\u5bb6\u5f00\u59cb\u63a8\u5e7f\u65b0\u7684\u52a0\u5f3a\u9488\u6218\u7565\uff0c\u65b0\u51a0\u75ab\u82d7\u7684\u63a8\u5e7f\u5b8c\u6210\u56fd\u5bb6\u91c7\u8d2d\u4e4b\u540e\uff0c\u968f\u7740\u65f6\u95f4\u63a8\u79fb\uff0c\u5728\u6f5c\u5728\u81ea\u8d39\u5e02\u573a\u73af\u5883\u4e0b\u5c06\u8fce\u6765\u4e00\u4e2a\u6709\u5438\u5f15\u529b\u7684\u5e74\u5ea6\u52a0\u5f3a\u9488\u5e02\u573a\uff0c\u7c7b\u4f3c\u4e8e\u5b63\u8282\u6027\u6d41\u611f\u75ab\u82d7\u63a5\u79cd\u5e02\u573a\uff0c\u800c\u4f18\u8d28\u7684\u75ab\u82d7\u4ea7\u54c1\u4f8b\u5982\u4e09\u53f6\u8349\u751f\u7269\u8054\u5408\u4f50\u5242\u7684\u86cb\u767d\u65b0\u51a0\u75ab\u82d7\u5c06\u53d7\u5230\u9752\u7750\u3002<\/p>\n

\u3000\u3000\u951a\u5b9a\u672a\u6765\uff0c\u79ef\u6781\u8c03\u6574\u4e1a\u52a1\u5e03\u5c40\u4e0e\u7ba1\u7ebf\u6218\u7565<\/strong><\/p>\n

\u3000\u3000\u5728\u6700\u65b0\u7684\u6d88\u606f\u4e2d\uff0c\u5c24\u4e3a\u5f15\u8d77\u5927\u5bb6\u5173\u6ce8\u7684\u662f\uff0c\u4e09\u53f6\u8349\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u517c\u6267\u884c\u8463\u4e8b\u6881\u679c\u5bf9\u516c\u53f8\u672a\u6765\u53d1\u5c55\u660e\u786e\u5b9a\u4f4d\uff1a\u201c\u4e09\u53f6\u8349\u751f\u7269\u5df2\u5efa\u7acb\u8d77\u4e2d\u56fd\u548c\u5168\u7403\u7814\u53d1\u56e2\u961f\uff0c\u4ee5\u53ca\u751f\u4ea7\u548c\u5546\u4e1a\u5316\u80fd\u529b\uff0c\u5373\u5c06\u6210\u957f\u4e3a\u4e00\u5bb6\u72ec\u7279\u7684\u3001\u4e13\u6ce8\u4e8e\u75ab\u82d7\u7684\u7efc\u5408\u578b\u516c\u53f8\u3002\u6211\u4eec\u671f\u671b\u6301\u7eed\u6253\u9020\u521b\u65b0\u3001\u4e13\u6ce8\u75ab\u82d7\u5e76\u6709\u671b\u521b\u9020\u8fd1\u671f\u4ef7\u503c\u7684\u7ba1\u7ebf\u3002\u201d<\/p>\n

\"\u81ea\u52a8\u8349\u7a3f\"<\/center><\/p>\n

\u3000\u3000\u4e09\u53f6\u8349\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u517c\u6267\u884c\u8463\u4e8b\u6881\u679c<\/p>\n

\u3000\u3000\u57fa\u4e8e\u4ee5\u75ab\u82d7\u4e3a\u6838\u5fc3\u7684\u6218\u7565\u5b9a\u4f4d\uff0c\u4e09\u53f6\u8349\u751f\u7269\u5c06\u52a0\u5927\u63d0\u5347\u81ea\u4e3b\u7814\u53d1\u80fd\u529b\uff0c\u51ed\u501fTrimer-Tag™\u6280\u672f\uff0c\u4ee5\u53ca\u65e2\u5f80\u6210\u529f\u7684\u56fd\u9645\u5408\u4f5c\u7ecf\u5386\uff0c\u5efa\u7acb\u4e00\u4e2a\u521b\u65b0\u548c\u6f5c\u5728\u9886\u5148\u7684\u75ab\u82d7\u7ec4\u5408\u3002<\/p>\n

\u5728\u5bcc\u6709\u524d\u666f\u7684\u7ba1\u7ebf\u4e2d\uff0cSCB-2020S(\u57fa\u4e8e\u8d1d\u5854\u53d8\u5f02\u682a\u548c\u539f\u59cb\u6bd2\u682a\u5d4c\u5408\u578b\u7684\u65b0\u51a0\u5019\u9009\u75ab\u82d7)\uff0c\u662f\u6f5c\u5728\u7684\u4e0b\u4e00\u4ee3\u5e7f\u8c31\u65b0\u51a0\u5019\u9009\u75ab\u82d7\u3002\u76ee\u524d\u5728\u5357\u975e\u5f00\u5c55\u7684I\u671f\u4e34\u5e8a\u5b9e\u9a8c\u4e2d\uff0c\u5c06\u628aSCB-2020S\u8054\u5408CAS-1\u4f50\u5242\u4e00\u8d77\u8fdb\u884c\u8bc4\u4f30\uff0cCAS-1\u662f\u4e09\u53f6\u8349\u751f\u7269\u81ea\u4e3b\u7814\u53d1\u7684\u4f50\u5242\u7cfb\u7edf\u3002\u4e09\u53f6\u8349\u751f\u7269\u5168\u7403\u7814\u53d1\u603b\u88c1\u502a\u542f\u777f\u535a\u58eb\u8868\u793a\uff1a\u201cSCB-2020S\u540c\u6837\u4ee4\u4eba\u5174\u594b\uff0c\u8fd9\u662f\u7b2c\u4e8c\u4ee3\u53ef\u80fd\u5177\u6709\u5e7f\u6cdb\u4fdd\u62a4\u4f5c\u7528\u7684\u65b0\u51a0\u5019\u9009\u75ab\u82d7\uff0c\u9884\u8ba1\u5c06\u57282022\u5e74\u7b2c\u56db\u5b63\u5ea6\u83b7\u5f97\u4e34\u5e8a\u7ed3\u679c\uff0c\u5e76\u7ee7\u7eed\u5e94\u7528\u6211\u4eec\u7ecf\u8fc7\u9a8c\u8bc1\u7684Trimer-Tag™\u6280\u672f\u5e73\u53f0\u6765\u5f00\u53d1\u521b\u65b0\u548c\u6709\u5f71\u54cd\u529b\u7684\u75ab\u82d7\u3002\u201d<\/p>\n

\"\u81ea\u52a8\u8349\u7a3f\"<\/center><\/p>\n

\u3000\u3000\u4e09\u53f6\u8349\u751f\u7269\u6d59\u6c5f\u957f\u5174\u751f\u4ea7\u57fa\u5730<\/p>\n

\u3000\u3000\u4e0e\u6b64\u540c\u65f6\uff0c\u4e09\u53f6\u8349\u751f\u7269\u8fd8\u5728\u79ef\u6781\u8bc4\u4f30\u4e2d\u540e\u671f\u521b\u65b0\u75ab\u82d7\u8d44\u4ea7\u7684\u4e1a\u52a1\u53d1\u5c55\u673a\u4f1a\u3002\u8fd9\u4e9b\u75ab\u82d7\u8d44\u4ea7\u53ef\u80fd\u4e0e\u5185\u90e8\u7684\u4e09\u805a\u4f53\u5316\u75ab\u82d7\u7ec4\u5408\u4ea7\u751f\u534f\u540c\u4f5c\u7528\uff0c\u5e76\u6709\u671b\u5e26\u6765\u8fd1\u671f\u521b\u9020\u6f5c\u5728\u4ef7\u503c\u7684\u673a\u4f1a\u3002<\/p>\n

\u3000\u3000\u5173\u4e8eSCB-2019 (CpG 1018\/\u94dd\u4f50\u5242)<\/strong><\/p>\n

\"\u81ea\u52a8\u8349\u7a3f\"<\/center>\u3000\u3000\u4e09\u53f6\u8349\u751f\u7269\u5f00\u53d1\u4e86SCB-2019\u6297\u539f\uff0c\u5b83\u662f\u4e00\u79cd\u57fa\u4e8eSARS-CoV-2(\u65b0\u51a0\u75c5\u6bd2)\u539f\u59cb\u6bd2\u682aS\u86cb\u767d\u7684\u7a33\u5b9a\u7684\u4e09\u805a\u4f53\u7ed3\u6784\u878d\u5408\u86cb\u767d(S-\u4e09\u805a\u4f53™)\u3002\u4e09\u53f6\u8349\u751f\u7269\u7684\u65b0\u51a0\u5019\u9009\u75ab\u82d7SCB-2019 (CpG 1018\/\u94dd\u4f50\u5242)\u662f\u7531SCB-2019\u6297\u539f\u8054\u5408\u4e24\u79cd\u4f50\u5242\uff0c\u5373Dynavax(\u7eb3\u65af\u8fbe\u514b\uff1aDVAX)\u7684CpG 1018\u4f50\u5242\u53ca\u6c22\u6c27\u5316\u94dd(\u94dd\u4f50\u5242)\u7ec4\u6210\u3002\u904d\u5e03\u5168\u7403\u4e94\u4e2a\u56fd\u5bb6\uff0c\u5165\u7ec4\u8d85\u8fc73\u4e07\u540d\u53d7\u8bd5\u8005\u7684\u201cSPECTRA\u201dII\/III\u671f\u6570\u636e\u663e\u793a\uff0cSCB-2019(CpG 1018\/\u94dd\u4f50\u5242)\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5bf9\u9884\u9632\u4efb\u4f55\u6bd2\u682a\u5f15\u8d77\u7684\u91cd\u5ea6\u548c\u9700\u4f4f\u9662\u6cbb\u7597\u7684\u65b0\u51a0\u80ba\u708e(COVID-19)\u4fdd\u62a4\u6548\u529b\u4e3a100%\uff0c\u5e76\u5177\u6709\u6f5c\u5728\u4e1a\u754c\u9886\u5148\u7684\u5b89\u5168\u6027\u3002\u4e09\u53f6\u8349\u751f\u7269\u6b63\u5728\u5f00\u53d1SCB-2019(CpG1018\/\u94dd\u4f50\u5242)\uff0c\u6709\u671b\u4f7f\u5176\u5728\u4e0d\u8003\u8651\u57fa\u7840\u514d\u75ab\u75ab\u82d7\u7684\u6280\u672f\u8def\u7ebf\u4ee5\u53ca\u65e2\u5f80\u65b0\u51a0\u611f\u67d3\u53f2\u7684\u60c5\u51b5\u4e0b\uff0c\u5747\u53ef\u4f5c\u4e3a\u52a0\u5f3a\u9488\u4f7f\u7528\u3002\u8fc4\u4eca\uff0c\u8fd9\u4e9b\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u7ecf\u663e\u793aSCB-2019(CpG1018\/\u94dd\u4f50\u5242)\u5bf9\u5305\u62ec\u5965\u5bc6\u514b\u620e\u5728\u5185\u7684\u53d8\u5f02\u682a\u8bf1\u5bfc\u4e86\u5f3a\u52b2\u7684\u514d\u75ab\u5e94\u7b54\u3002\u4e09\u53f6\u8349\u751f\u7269\u6b63\u5728\u5bfb\u6c42\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u3001\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u548c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u5bf9SCB-2019\u7684\u6ce8\u518c\u6279\u51c6\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u8fd1\u65e5\uff0c\u4e09\u53f6\u8349\u751f\u7269\u516c\u5e032022\u5e74\u516c\u53f8\u4e1a\u52a1\u91cd\u8981\u8fdb\u5c55\uff1a \u9996\u8981\u7684\u65b0\u51a0\u5019\u9009\u75ab\u82d7SCB-2019(CpG 1018\/\u94dd\u4f50\u5242…<\/p>\n

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